EQ-5D-5L Value Sets
Update August 2016: link to new Japanese publication added, see below.
The EuroQol Group launched a 5-level version of the EQ-5D descriptive system, the EQ-5D-5L (M. Herdman et al. Qual Life Res DOI 10.1007/s11136-011-99031). In developing the 5L, the 5-dimensional structure of the original EQ-5D-3L was retained but the levels on each dimension were expanded to 5-levels based on qualitative and quantitative studies conducted by the EuroQol Group. The labels for each of the dimensions are: no problems, slight problems, moderate problems, severe problems and unable to/extreme problems. [Please note that the EQ-VAS is still an integral part of the EQ-5D-5L but has been adapted to make it more user friendly].
Index-based values (‘utilities’) are a major feature of the EQ-5D instrument, facilitating the calculation of quality-adjusted life years (QALYs) that are used to inform economic evaluations of health care interventions. Studies that directly elicit preferences from general population samples to derive value sets for the EQ-5D-5L are under development in a number of countries; however, these studies will take time to complete and for results to be disseminated.
Available EQ-5D-5L value sets
Devlin N et al. Valuing Health-Related Quality of Life: An EQ-5D-5L Value Set for England (this tariff replaces the preliminary tariff that was presented on July 2015)
Kim SH et al. The EQ-5D-5L valuation study in Korea (only open to subscribers)
Crosswalk value sets for the EQ-5D-5L
In the interim, the EuroQol Group coordinated a study that administered both the 3-level and 5-level versions of the EQ-5D, in order to develop a “crosswalk” between the EQ-5D-3L value sets and the new EQ-5D-5L descriptive system, resulting in crosswalk value sets for the EQ-5D-5L. A total of 3691 respondents completed both the 3L and 5L across 6 countries: Denmark, England, Italy, the Netherlands, Poland and Scotland. Different subgroups were targeted, and in most countries, a screening protocol was implemented to ensure that a broad spectrum of levels of health would be captured across the dimensions of EQ-5D for both the 5L and 3L descriptive systems.
Crosswalk value sets for the EQ-5D-5L are currently available for the following countries: Denmark, France, Germany, Japan, the Netherlands, Spain, Thailand, UK, US and Zimbabwe. A scientific publication describing the methodology behind the study in detail is published in Value In Health Journal. A more detailed description of the crosswalk model and methodology, and the actual index values can be downloaded below:
A tool "EQ-5D-5L Crosswalk Index Value Calculator" calculates the crosswalk index values for the EQ-5D-5L dimension scores and can be downloaded below:
- EQ-5D-5L Crosswalk Index Value Calculator
- EQ-5D-5L Crosswalk Index Value Calculator (for Apple devices)
When referencing the source of crosswalk index values based on the use of this calculator, please cite: "van Hout B, Janssen MF, et al. Interim scoring for the EQ-5D-5L: Mapping the EQ-5D-5L to EQ-5D-3L value sets. Value in Health 2012 Jul-Aug;15(5):708-15."